Ruud went the distance at the Swiss Open earlier this month, beating Matteo Berrettini in the final to lift the crown.
Alex Molcan and Thiago Monteiro are scheduled to face one another in the first round match of the US Open 2022 on Tuesday, August 30.
On Monday in the opening round of the 2022 US open Arthur Rinderknech of France will face his compatriot Quentin Halys.
Medvedev was banned for participating at Wimbledon as organisers had barred Russian and Belarusian players owing to Russia's invasion of Ukraine.
Daria Kasatkina and Harriet Dart are scheduled to face one another in the first round match of the US Open 2022 on Tuesday, August 30.
On Monday, Argentina's No. 24 seed Francisco Cerundolo will compete against 2012 US Open champion Andy Murray.
Cori Gauff and Léolia Jeanjean are scheduled to face one another in the first round match of the US Open 2022 on Tuesday, August 30.
Simona Halep and Daria Snigur are scheduled to face one another in the first round match of the US Open 2022 on Tuesday, August 30.
Marin Cilic and Maximilian Marterer are scheduled to face one another in the first round match of the US Open 2022 on Tuesday, August 30.
Nick Kyrgios and Thanasi Kokkinakis are scheduled to face one another in the first round match of the US Open 2022 on Monday, August 29.