Monday's opening round of the 2022 US Open will pit world number 17 Caroline Garcia against 90th-ranked Kamilla Rakhimova of Russia.
On Monday, American Ann Li will take on Colombian Camila Osorio in the opening round of the 2022 US Open.
On Monday, Rebecca Peterson of Sweden will play Anna Kalinskaya of Russia in the opening round of the 2022 US Open.
Nadal has been exceptional in Grand Slams this seasons, winning the Australian Open and the French Open.
The world no. 1 will be hoping for a turn of fortunes at the fourth and final Grand Slam of the year.
Kudermetova participated in the Canadian Open where she lost in the round of 64 against Ajla Tomljanovic.
Most recently, Sakkari took part in the Cincinnati Masters but was eliminated in the very first round by Caroline Garcia.
On Monday at the US Open, 2020 US Open winner Dominic Thiem will square off against Pablo Carreno Busta, a two-time semifinalist.
Auger-Aliassime's best performance was at the Los Cabos Open where he made it through to the semi-final where he was beaten by Cameron Norrie.
Leylah Fernandez, ranked 14th in the world, will face Oceane Dodin, ranked 99th, in the opening round of the 2022 US Open on Tuesday.