This year, Jabeur became the first Arab and African player to reach a women's singles Grand Slam final, and she repeated the feat at the US Open.
Iga Swiatek had one of the most successful tennis seasons in history, winning 67 matches and eight tournaments, including two Grand Slams.
Jabeur did win the first set but a determined Sabalenka held her nerve and delivered an inspirational performance to hand the reigning Madrid Open champion a defeat.
Jabuer, the top seed in the Nancy Richey group, has only played one tournament since reaching the US Open final.
There is no surprise that world no. 1 and top seed Iga Swiatek is the strongest favourite for the title. However, she will have her work cut out for her.
Iga Swiatek and Ons Jabeur are scheduled to face one another in the finals of the US Open 2022 on Sunday, September 11.
Jabeur, who was involved in the final of Wimbledon earlier this year, beat Australia's Ajla Tomljanovic in the quarter-final.
Ons Jabeur and Ajla Tomljanovic are scheduled to face one another in the quarter-final of the US Open 2022 on Tuesday, September 6.
Ons Jabeur and Veronika Kudermetova are scheduled to face one another in a round of 16 match of the US Open 2022 on Sunday, September 4.
The Tunsian picked up a 7-5, 6-2 win over Brengle, scoring five aces and converting six out of eight break points.