Gerard Moreno has been in sensational form for Villareal, making his presence felt with excellent performances.
Atletico Madrid have won four of the last five La Liga games in Valladolid, drawing the last one in October 2019.
Karim Benzema was banned from the French national team since 2015 by the football federation because of the "sex tape" scandal.
Real Madrid beat Granada 4-2 on Thursday to keep the pressure on league leaders Atletico Madrid, who beat Real Sociedad 2-1 at home in the other match of the day.
Real Madrid scored a late equalizer against Sevilla at the Di Stefano stadium on Sunday night to secure a 2-2 draw.
Karim Benzema has scored 71 goals in the UEFA Champions League sitting on level with Raúl González's tally.
Chelsea host Real Madrid in the Champions League semi-final second leg fixture at the Stamford Bridge on Wednesday night.
Christian Pulisic scored the crucial goal but Karim Benzema got the equalizer for Real Madrid in a 1-1 draw at the Alfredo Di Stefano stadium.
During his time at Real Madrid, Ronaldo came up with the noble gesture to help his teammate find his goal-scoring touch