With the Premier League fixtures coming thick and fast in the demanding winter period, Klopp would like to see his club maintain their recent good run of form.
The Champions League last-16 draw was redone after mistakes at the first attempt saw Manchester United paired with Villarreal.
Liverpool became the first English club to win all six of their games in a Champions League group phase.
Greenwood scored a stunning opener against Young Boys on Wednesday night, but United had to settle for a draw in the Champions League match.
Having already qualified top of the group after beating Villarreal in their last match, the midweek game will mean more for the opponents than for the Red Devils.
Interim manager Ralf Rangnick believes the group closer against Young Boys is a great chance to get to know more of his players.
The German was assisted by technical director Darren Fletcher and first-team coach Kieran McKenna during his first match in charge.
Ralf Rangnick, head of sports and development at Lokomotiv Moscow, is being reported by various sources as the front-runner to become Manchester United’s interim manager.
After a debut 2020-21 season at Liverpool that was afflicted by injuries and COVID-19, Tsimikas has gained more regular opportunities in the team this term.
The Reds face their third match in the space of a week when Southampton visit Anfield on Saturday in the Premier League.