Man City are not that far behind the Gunners in the standings. As things stand, City have 45 points from 20 games to sit second in the table.
With 50 points from 19 games, Mikel Arteta’s side have been nearly unstoppable this campaign.
For Arsenal, this game is largely about getting revenge on the only side that has beaten them in the league this campaign.
Manchester United nearly made it 10 wins in a row in all competitions, however, a late draw at Crystal Palace forced them to end that winning streak.
Tottenham Hotspur will host Arsenal in a Premier League fixture at the Tottenham Hotspur Stadium on Sunday evening.
Arsenal's draw at home to Newcastle United in their last match has helped second-placed Manchester City cut the deficit at top to five points.
Meanwhile, Oxford United are going through an inconsistent season in League One. They are currently placed 15th with 29 points from 24 games.
The Gunners have been deserved leaders till now, while Newcastle have surprised many to be currently placed in the top four positions.
The Gunners have been excellent this campaign, losing just once so far in the league against Manchester United at Old Trafford.
Brighton & Hove Albion will host Arsenal in an English Premier League fixture on Saturday.