Spezia will take on Hellas Verona in the Serie A relegation playoff at Stadio Citta del Tricolore on Sunday.
Both clubs in their respective leagues have been wobbly and unreliable, having dropped points in all three of their most recent matches.
Juventus will be looking to get back to winning ways when they host Spezia in a Serie A fixture at the Allianz Stadium on Wednesday night.
Inter Milan will host spezia in a Serie A fixture at the San Siro on Saturday night.
Bologna beat Spezia 2-1 in the Serie A fixture at Renato Dall'Ara in Monday.
AS Roma defeated Spezia 2-0 in the Serie A fixture at Olimpico on Monday.
Inter Milan and Atalanta played out a thrilling 2-2 draw in the Serie A fixture at San Siro on Saturday.
Juventus produced a second-half fight back to squeeze out a 3-2 win against Spezia at Alberto Picco on Wednesday.
Empoli stun Juventus through Leonardo Mancuso's first half strike while Lazio thrash Spezia 6-1 at home courtesy of Ciro Immobile's hat-trick.
AC Milan began their 2021/22 Serie A campaign with a 1-0 win over Sampdoria courtesy of Brahim Diaz' 9th minute strike.