The 28-year-old was last seen in action in a 2-2 draw with Atalanta in early November before suffering an injury while on international duty.
The full-back had made 35 appearances in three seasons at United before 2021/22, however, his fortunes seem to have been changed now.
The young English forward was at the end of a few bright moments in attack as the Reds were 0-0 with the visiting team during his substitution.
Wolves outplayed United in almost every department and were the better team for most parts of the game. They were full value for the three points.
Ahead of the tricky encounter with Wolves, Rangnick emphasised the importance of keeping the unbeaten eight-game stretch going.
At the age of 36, there were a lot of doubts about whether Ronaldo can live up to the expectations, but the former Real Madrid forward has silenced his critics in some style.
Cavani came off the bench to score the equaliser at St James’ Park before starting in the victory over Burnley last time out.
Midway through the second half against Burnley, Bailly went to the ground and was quickly replaced by substitute Raphael Varane.
McTominay’s Man-of-the-Match performance at Old Trafford saw the Scotland international score the opener in the 3-1 Premier League victory.
Goals from Scott McTominay, an own-goal by Ben Mee and a third by Cristiano Ronaldo put the Reds 3-0 up before Aaron Lennon quickly pulled one back.