Eddie Howe's side will be entering this game on the back of registering a 1-0 victory in the first leg away from home.
Newcastle United’s position in the Premier League table and their impeccable defensive record makes it difficult for any side to beat them.
Newcastle have defied all the odds to be deservedly sitting third in the Premier League table with 39 points from 20 games.
The bottom-placed Saints have performed well below-par this campaign. With just 15 points from 20 games, they are placed at the 20th spot in the table.
Newcastle United have conceded just 11 goals in the league till now, which is the best defensive record amongst all teams in the division.
Newcastle have 38 points from 19 games to be sitting fourth in the table. They are only one point behind third-placed Manchester United.
Two of Premier League’s in-form side’s Newcastle United and Fulham will go head to head at the St James Park on Sunday.
Newcastle United will host Leicester City in an EFL Cup quarter-final fixture at St James’s Park on Tuesday night.
Newcastle United will travel to Hilborough to take on Sheffield Wednesday in an FA Cup third round fixture on Saturday.
The Gunners have been deserved leaders till now, while Newcastle have surprised many to be currently placed in the top four positions.