India's top women's tennis player Ankita Raina defeated Australian Arina Rodionova in a first round French Open qualifier.
The teenager is set to be the youngest seed at the French Open in 15 years, since Nicole Vaidisova was seeded at the Wimbledon in 2006.
Swiatek wrote her name in the history books when she became the lowest-ranked woman to win the French Open the previous year at rank 54.
Canada's Denis Shapovalov announced his that he would not be taking part in the French Open 2021 due to a shoulder injury.
Wawrinka, who has a 44-15 record in the French Open, won the title back in 2015 and finished runner-up on the Parisian terre battue in 2017.
Rafael Nadal has joined Roger Federer and Jimmy Connors as the other players to have reached the quarterfinal stage of a tournament more than 15 times.
American teen Coco Gauff on Saturday did a clean sweep of both the women's singles and doubles titles in the Emilia-Romagna Open.
She had sustained a tear in her left calf during her recent Italian Open Round of 32 match against German player Angelique Kerber in Rome.
Rafael Nadal believes that a win in the Rome ATP 1000 tournament is no guarantee of success at the French Open.
Novak Djokovic lost in the final of the Italian Open to Rafael Nadal in three tough sets.