Milwaukee Bucks never trailed while racing to a 77-38 halftime advantage and handing the Warriors their fourth loss in five games..
Lillard has already missed 11 games thus far this season, and the injury bothered him while playing for Team USA at the Olympics.
''For the second game in a row, our defense let us down,'' Los Angeles Lakers coach Frank Vogel said after the loss.
Altman inherited Cleveland's GM job when David Griffin stepped down and was thrown into the fire to figure out a trade for Kyrie Irving.
For the Grizzlies and Morant, they kept their winning streak alive and moved even closer to the third spot in the Western Conference.
Thanks to Embiid, the Sixers extended their winning streak to a season-long seven games, and improved to 23-16.
Klay Thompson finished with 17 points on 7-of-18 shooting, including 3 of 8 from 3, in the 19 minutes of action.
Cleveland led going into the fourth quarter, fell behind by three, then went on a 14-2 run to take a comfortable lead.
The Portland Trail Blazers were without Damian Lillard, out with lower abdominal tendinopathy, and backcourt teammate CJ McCollum.
LaMelo Ball has been terrific as a playmaker since joining the Hornets as the No. 3 overall pick in the 2020 NBA draft.