Alpine has been undergoing a major re-organisation process spearheaded by the team's CEO Laurent Rossi, which began on January 13.
The Enstone-based team enjoyed a breakthrough 2021 Formula 1 season, with Esteban Ocon winning his first Grand Prix in Hungary.
Alain Prost, who recently departed from his role as Alpine's non-executive director, said that relations with Laurent Rossi just became more difficult.
Fernando Alonso is currently on a six-race scoring streak with a season-best finish of fourth at the Hungarian Grand Prix.
Guanyu Zhou will become only the second Chinese driver to get behind the wheel in a Formula 1 practice session.