Luton Town and Wigan Athletic will be coming up against each other in the round three of the FA Cup 2022/23.
A convincing 4-0 triumph at Crystal Palace in their last match has put Spurs right back into the mix for Champions League qualification.
Brentford are going through a good phase of late by producing some eye-catching results, which includes victories over Liverpool and Manchester City.
Portsmouth are going through a poor run of form in League One. They are sitting 12th with 31 points from 22 games.
Brentford overcame champions Manchester City and Liverpool in recent games. They are sitting ninth in the table with 26 points from 18 matches.
Forest Green Rovers will host Birmingham City in a n FA cup third round fixture at The New Lawn on Saturday.
Reading will host Watford in a FA Cup third round fixture at Madejski Stadium on Saturday afternoon.
Preston North End will host Huddersfield Town in an FA Cup third round match at Deepdale on Saturday afternoon.
Leicester will begin their FA Cup campaign with a trip to Priestfield to take on Gillingham on Saturday afternoon.
Crystal Palace will be commencing this season's FA Cup journey against Southampton on Saturday afternoon.