USA will host Uruguay in an international friendly in Kansas City on Sunday.
Chelsea have 65 points from 32 games, while West Ham missed the opportunity to climb above Manchester United. They have 52 points from 34 matches.
The USA international seems to have found his form after producing a goal and an assist during the 4-0 victory at Burnley on Saturday.
Kai Havertz scored a double as Chelsea defeated Burnley 4-0 in the Premier League fixture at Turf Moor on Saturday.
Liverpool defeated Chelsea on penalties to win the Carabao Cup.
Chelsea defeated Lille 2-0 in the Champions League last-16 first leg tie at Stamford Bridge on Tuesday.
The game will come too early for the return of Christian Pulisic, while Antonio Rudiger picked up an injury on international duty.
Kante’s absence will be a massive blow to the Blues ahead of their clash with Juventus in the Champions League.
Christian Pulisic will miss Chelsea’s clash with Arsenal on Sunday after testing positive for COVID-19, manager Thomas Tuchel has confirmed.
After winning the UEFA Super Cup in the midweek over Villarreal, Chelsea started the new Premier League season with a 3-0 win.