Argentina were without Lionel Messi but Angel di Maria and Lautaro Martinez scored for the visitors to take all three points against Chile in the world cup qualifier.
Brazil beat Chile 1-0 courtesy of a Lucas Paqueta's strike whereas Peru got the better of Paraguay on penalties after a six goal thriller to go through to the last-4.
Uruguay beat Bolivia 2-0 at Arena Pantanal courtesy of an own goal from Jairo Quinteros and a second half strike from Edinson Cavani.
Argentina beat Uruguay 1-0 at Brasilia on Friday courtesy of Guido Rodriguez's lone goal in the 13th minute and secured three points.
Argentina were held to a 1-1 draw against Chile in their Copa America 2021 opening match despite Lionel Messi scoring a stunning free-kick goal.