With a top-four finish now guaranteed, Barcelona will host Celta Vigo in the La Liga fixture at Camp Nou on Tuesday evening.
Karim Benzema has been in prolific goal scoring form for Real Madrid this season, having netted a brace against Celta Vigo on Saturday.
La Liga returned after the Christmas break this weekend, and Spain's giants had contrasting fortunes in their respective fixtures.
Luiz Suarez scored a late double as Atletico Madrid came from behind to beat Getafe 2-1 on Tuesday.
Sevilla beat Celta Vigo 3-4 on Monday to stay alive in the title race.