Lionel Messi scored his maiden goal for Paris Saint-Germain in the 2-0 win over Manchester City.
While City won on aggregate in last season's meetings, Pep has warned that those results will have little bearing on the upcoming matches.
While several had predicted a rift in their relationship, Pochettino confirmed that Messi had actually picked up a knee injury.
Neymar canceled out Lucas Pacqueta's opener before substitute Mauro Icardi scored an injury time winner for PSG against Lyon.
Thirteen clubs from Europe's top leagues wanted to form a breakaway European competition earlier in the year.
Manchester City are up against Lionel Messi-powered Paris Saint-Germain in Group A, with Liverpool set to take on Atletico Madrid yet again.
Real Madrid have made a 160 million euros opening bid for Paris Saint-Germain striker Kylian Mbappe, according to multiple reports in Europe.
Bayern Munich beat Paris Saint-Germain 1-0 in the final of the 2020 UEFA Champions League, thus completing their second continental treble.
A blistering PSG counterattack finished off by substitute Angel Di Maria's deft lob ensured the Parisians held on to claim three points.
The Argentine superstar, who left Barcelona after 21 years at the club last week, joined PSG on a two-year deal on Tuesday.