Kevin Durant had 17 points in the third quarter to help Brooklyn break open a game that was tied at 71-all early in the quarter.
The Portland Trail Blazers were without Damian Lillard, out with lower abdominal tendinopathy, and backcourt teammate CJ McCollum.
Lance Stephenson became the first player in NBA history to score 20 points off the bench in the first quarter.
Kyrie Irving back under such circumstances will present some issues to the Nets, they'll have to change their game-plan frequently.
Even without Kyrie Irving, the Nets are still performing at a high level, sitting at 19-8 and in first place in the Eastern Conference.
Adams said in an interview with CNN on Friday that the city will not be changing the COVID-19 vaccination rules that are currently in place.
Brooklyn Nets has been without Irving due to his unvaccinated status, and it's unclear when or if he'll play this season.
Protesters chanted "let Kyrie play" while holding up signs that read "Stand with Kyrie" ahead of Brooklyn's matchup with Charlotte Hornets.
"The contract, the money it's gonna be there. I don't plan on leaving this organization and the situation that we have," Harden said.
Kyrie Irving won't be permitted to practice with the team or play in road games until he is a "full participant".