| No. of times Played | 26 |
|
|
|
| Win % | 23% |
| H2H |
| Last Played | 2018 | First Played | 2004 |
| Tournament | Australian Open | Tournament | Athens Olympics |
| Round | Quarter-Finals | Round | Round of 32 |
| Winner | Roger Federer | Winner | Tomas Berdych |
| Score | 76 | Score | 64 57 57 |
| No. of times Played | 51 |
|
|
|
| Win % | 55% |
| H2H |
| Last Played | 2020 | First Played | 2006 |
| Tournament | Australian Open | Tournament | SUI v. SCG WG PO |
| Round | Semi-Finals | Round | Round Robin |
| Winner | Novak Djokovic | Winner | Roger Federer |
| Score | 67 | Score | 63 62 63 |
| No. of times Played | 3 |
|
|
|
| Win % | 0% |
| H2H |
| Last Played | 2019 | First Played | 2018 |
| Tournament | ATP Masters 1000 Miami | Tournament | Basel |
| Round | Round of 16 | Round | Semi-Finals |
| Winner | Roger Federer | Winner | Roger Federer |
| Score | 64 62 | Score | 61 64 |
| No. of times Played | 7 |
|
|
|
| Win % | 57% |
| H2H |
| Last Played | 2019 | First Played | 2016 |
| Tournament | ATP Masters 1000 Shanghai | Tournament | Halle |
| Round | Quarter-Finals | Round | Semi-Finals |
| Winner | Alexander Zverev | Winner | Alexander Zverev |
| Score | 36 76 | Score | 67 |
| No. of times Played | 41 |
|
|
|
| Win % | 59% |
| H2H |
| Last Played | 2019 | First Played | 2004 |
| Tournament | Wimbledon | Tournament | ATP Masters 1000 Miami |
| Round | Semi-Finals | Round | Round of 32 |
| Winner | Roger Federer | Winner | Rafael Nadal |
| Score | 76 | Score | 36 36 |
| No. of times Played | 2 |
|
|
|
| Win % | 50% |
| H2H |
| Last Played | 2021 | First Played | 2019 |
| Tournament | Wimbledon | Tournament | ATP Masters 1000 Indian Wells |
| Round | Quarter-Finals | Round | Quarter-Finals |
| Winner | Hubert Hurkacz | Winner | Roger Federer |
| Score | 36 67 | Score | 64 64 |
| No. of times Played | 2 |
|
|
|
| Win % | 0% |
| H2H |
| Last Played | 2021 | First Played | 2019 |
| Tournament | Wimbledon | Tournament | Roland Garros |
| Round | Round of 16 | Round | Round of 128 |
| Winner | Roger Federer | Winner | Roger Federer |
| Score | 75 64 62 | Score | 62 64 64 |
| No. of times Played | 8 |
|
|
|
| Win % | 13% |
| H2H |
| Last Played | 2019 | First Played | 2013 |
| Tournament | US Open | Tournament | Basel |
| Round | Quarter-Finals | Round | Quarter-Finals |
| Winner | Grigor Dimitrov | Winner | Roger Federer |
| Score | 63 46 63 46 26 | Score | 63 76 |
| No. of times Played | 11 |
|
|
|
| Win % | 9% |
| H2H |
| Last Played | 2021 | First Played | 2008 |
| Tournament | Roland Garros | Tournament | ATP Masters 1000 Paris |
| Round | Round of 64 | Round | Round of 16 |
| Winner | Roger Federer | Winner | Roger Federer |
| Score | 62 26 76 | Score | 63 64 |
| No. of times Played | 7 |
|
|
|
| Win % | 71% |
| H2H |
| Last Played | 2019 | First Played | 2016 |
| Tournament | Nitto ATP Finals | Tournament | Stuttgart |
| Round | Round Robin | Round | Semi-Finals |
| Winner | Dominic Thiem | Winner | Dominic Thiem |
| Score | 57 57 | Score | 63 67 |
| No. of times Played | 11 |
|
|
|
| Win % | 27% |
| H2H |
| Last Played | 2019 | First Played | 2011 |
| Tournament | Wimbledon | Tournament | Basel |
| Round | Quarter-Finals | Round | Finals |
| Winner | Roger Federer | Winner | Roger Federer |
| Score | 46 61 64 64 | Score | 61 63 |
| No. of times Played | 1 |
|
|
|
| Win % | 0% |
| H2H |
| Last Played | 2021 | First Played | 2021 |
| Tournament | Roland Garros | Tournament | Roland Garros |
| Round | Round of 32 | Round | Round of 32 |
| Winner | Roger Federer | Winner | Roger Federer |
| Score | 76 | Score | 76 |
| No. of times Played | 7 |
|
|
|
| Win % | 0% |
| H2H |
| Last Played | 2021 | First Played | 2011 |
| Tournament | Wimbledon | Tournament | ATP Masters 1000 Paris |
| Round | Round of 128 | Round | Round of 32 |
| Winner | Roger Federer | Winner | Roger Federer |
| Score | 64 67 | Score | 62 63 |
| No. of times Played | 21 |
|
|
|
| Win % | 10% |
| H2H |
| Last Played | 2021 | First Played | 2005 |
| Tournament | Wimbledon | Tournament | ATP Masters 1000 Hamburg |
| Round | Round of 64 | Round | Finals |
| Winner | Roger Federer | Winner | Roger Federer |
| Score | 76 | Score | 63 75 76 |
| No. of times Played | 25 |
|
|
|
| Win % | 44% |
| H2H |
| Last Played | 2015 | First Played | 2005 |
| Tournament | ATP Masters 1000 Cincinnati | Tournament | Bangkok |
| Round | Semi-Finals | Round | Finals |
| Winner | Roger Federer | Winner | Roger Federer |
| Score | 64 76 | Score | 63 75 |
| No. of times Played | 15 |
|
|
|
| Win % | 7% |
| H2H |
| Last Played | 2018 | First Played | 2007 |
| Tournament | Rotterdam | Tournament | ATP Masters 1000 Monte Carlo |
| Round | Semi-Finals | Round | Round of 32 |
| Winner | Roger Federer | Winner | Roger Federer |
| Score | 63 76 | Score | 76 |
| No. of times Played | 15 |
|
|
|
| Win % | 20% |
| H2H |
| Last Played | 2018 | First Played | 2012 |
| Tournament | ATP Masters 1000 Paris | Tournament | Halle |
| Round | Round of 32 | Round | Quarter-Finals |
| Winner | Roger Federer | Winner | Roger Federer |
| Score | (W/O) | Score | 67 |
| No. of times Played | 8 |
|
|
|
| Win % | 13% |
| H2H |
| Last Played | 2019 | First Played | 2015 |
| Tournament | Laver Cup | Tournament | ATP Masters 1000 Madrid |
| Round | Round Robin | Round | Round of 32 |
| Winner | Roger Federer | Winner | Nick Kyrgios |
| Score | 67 | Score | 76 |
| No. of times Played | 27 |
|
|
|
| Win % | 11% |
| H2H |
| Last Played | 2019 | First Played | 2005 |
| Tournament | Basel | Tournament | Rotterdam |
| Round | Quarter-Finals | Round | Round of 16 |
| Winner | Roger Federer | Winner | Roger Federer |
| Score | (W/O) | Score | 61 64 |
| No. of times Played | 25 |
|
|
|
| Win % | 28% |
| H2H |
| Last Played | 2018 | First Played | 2007 |
| Tournament | ATP Masters 1000 Indian Wells | Tournament | Basel |
| Round | Finals | Round | Round of 16 |
| Winner | Juan Martin del Potro | Winner | Roger Federer |
| Score | 46 76 | Score | 61 64 |
