Spain were due to play their final warm-up game before the Euros on Tuesday against Lithuania but will play the Spain Under-21s instead.
Following yesterday's draw between Barcelona and Atletico, Real Madrid have a chance to jump to the top of the table.
It’s all to play for in Spain and the stakes could scarcely be higher.
The encounter is expected to be quite interesting considering the pressure on both these teams to get a win at any cost.
Sevilla's record in away league games against Real Madrid is not kind reading for the team.
These cities were removed as they were no able to guarantee having enough fans in stadiums for the Euro 2020