The Swiss maestro won the first set, but was unable to build on the momentum as he lost the next two sets to Felix Auger-Aliassime in the second round.
Novak Djokovic, Roger Federer and Rafael Nadal could all end up with 20 Grand Slams if the Serb wins in Wimbledon.
The Swiss maestro won the opening set but failed to build on that momentum as he lost the remaining two sets to bow out of the tournament.
Novak Djokovic has won 19 Grand Slam titles but he is the only player to have won all four Grand Slams twice in the Open Era.
Novak Djokovic became the first player in the Open Era to win all four Grand Slams twice.
The World No.1 is the first male player in the Open Era and only the third player in history, to achieve the career Grand Slam twice.
Novak Djokovic won his first French Open title in 2016 to hold all four Grand Slams at the same time.
Novak Djokovic defeated Rafael Nadal for the second time in the French Open semi-final as he came one step closer to achieving history in Tennis.
After withdrawing from Roland Garros in the middle of the tournament, the Swiss star is back on familiar ground, hoping to be fully ready for Wimbledon.
The Serbian World No.1 has set up a mouth-watering semifinal clash with the 13-time Roland Garros champion Nadal on Friday.