Shapovalov was defeated by Sonego 7-6(4), 6-7(5), and 6-4 in the opening semifinal match
"The medical experts have advised that I am still not able to compete at my highest level following the foot injury l suffered in Naples," he said.
Berrettini struggled on service in the first set and was bothered by a foot pain, requiring a medical timeout at 2-5 in the opening in a hard-fought match at the ATP 250 event.
Matteo Berrettini and Taro Daniel are scheduled to face each other in the quarterfinal round of the 2022 ATP Napoli Open on October 21.
Matteo Berrettini and Roberto Carballés Baena will face each other in the second round of the 2022 ATP Firenze Open October 12.
The Djokovic/Berrettini pair will take on de Minaur and Sock on Saturday, September 24 in the fourth doubles match of the 2022 Laver Cup.
Matteo Berrettini will take on Felix Auger-Aliassime on Saturday, September 24 in the third singles match of the 2022 Laver Cup.
Casper Ruud rebounded from a mid-match hiccup to beat French lucky loser Corentin Moutet 6-1, 6-2, 6-7(4), 6-2 on Sunday to reach the US Open quarter-finals for the first time.
Matteo Berrettini vs Alejandro Davidovich are scheduled to face each other on Sunday, September 4 in the round of 16 of the 2022 US Open.
For the first time in six years, the 2012 champion won 14 of the final 15 games to advance to the third round in New York.