In a lopsided final, the Greek sensation defeated the British player in straight sets in the final on Sunday.
Third seed Ruud beats Denis Shapovalov in straight sets to win the Geneva Open final, while John Peers and Michael Venus capture the doubles title.
On the back of the straight-set victories, Tsitsipas will play Lorenzo Musetti for a place in the final.
The Austrian player suffered a shock 6-3, 6-2 defeat against Cameron Norrie at Lyon Open on Thursday.
The Greek player won the match in straight sets to reach the quarterfinals, where he will play Yoshihito Nishioka.
The Frenchman prevailed over Brazilian Thiago Seyboth Wild in a tightly-fought match in Lyon.