LeBron had 32 points, 11 rebounds and 11 assists for his third triple-double this season, and it was his fifth consecutive 30-point game.
The record is a testament to the longevity of James, who played in his first Christmas game as a rookie in 2003.
Harden and the Brooklyn Nets returned from a week-long COVID-19 hiatus to beat Los Angeles 122-115 Saturday night.
There were hopes that Durant could potentially be cleared based on a new agreement the league and the NBPA are working on.
Deandre Ayton had 19 points and 11 rebounds, and Booker scored 24 as the Suns won their fourth consecutive game.
LeBron James had 31 points, Carmelo Anthony added 21 and Russell Westbrook 20 as Los Angeles Lakers dropped its second straight game.
Horton-Tucker is currently the only member of the Lakers that is in the NBA's health and safety protocols.
LeBron James returned two negative PCR tests within 24 hours, and has been deemed eligible to play again by the league.
The suspension cost LeBron 284,004 dollars, according to reports. That alone is fairly significant, but it gets better for Los Angeles.
This is the first suspension of LeBron James' NBA career, and Sunday night's ejection was also just the second of his career.