Germany trailed Armenia at the top of Group J before kick-off, but that was soon forgotten as Serge Gnabry scored twice in the first 15 minutes.
Brazil thrash Germany 4-2 courtesy of a first half hat-trick from Richarlison at Yokohama on Thursday to kick start their Olympic gold defence.
Germany's team walked off the field with 5 minutes left because of alleged insults directed at 23-year-old defender Jordan Torunarigha.
With the likes of France and Portugal already out of the competition, Southgate will be looking to write his name in the history books.
Germany came from behind twice to draw 2-2 against Hungary and book a place in the last 16 of Euro 2020 in a thrilling encounter.
Germany take on Hungary at Allianz Arena on Wednesday aiming to qualify for the last 16 with a win whereas Hungary will be hoping for the surprise victory at the Bavarian city.
Germany and Porgutal were drawn alongside France and Hungary in Group F the ‘group of death’, and both these nations need this win.
Germany begin their final tournament with Joachim Low at the helm and they'll be keen to send the 61-year-old off with a winners' medal.
Considered by many as Germany's 'greatest treasure', Klose's exploits will present the national team with some much-needed motivation going into Euro 2020.
Freund termed France as the favourites to win Euro 2020 as they have the best squad by far in his opinion among all sides.