Rybanika broke Serena twice in the second to win the match 6-3, 7-5 in one hour and 17 minutes.
Both won their previous games in straight sets, and both seem to be in a similar vein of rich form going into the quarter-finals.
Pavlyuchenkova has returned to the last eight of the French Open for the first time in 10 years after a three-set victory over Azarenka.
The Russian wins his match in straight sets to set up a mouth-watering last-eight date with Stefanos Tsitsipas.
Roger Federer pulled out of the French Open, less than 12 hours after a difficult third-round victory.
With 6 years having passed since the day, let us look back at how Serena Williams created history by winning the 2015 French Open.
Tennis star Naomi Osaka took to social media to thank fans for their support after she pulled out of the ongoing French Open citing mental health concerns.
Nadal's fourth-round opponent will be Jannik Sinner in a match definitely promises to be an enthralling encounter.
The Serb played through his three sets with ease and dominance, and stamped his authority on the match from the get-go.
The German tennis player will face the Swiss maestro in an intriguing third-round clash on Saturday.