The Latvian smashed four aces, recorded 80% and 78% on the first and second serves respectively, and returned all five available break points to mark a dominant win.
The 2021 finalist Andreescu won their first-round match in Rome last year after Raducanu withdrew due to a lower back injury while trailing 6-2, 2-1.
The 20-year-old withdrew from Tuesday's Eisenhower Cup after pulling out of last week's ATX Open due to tonsillitis.
The biggest female talents, including Iga Swiatek, the world's best, as well as the up-and-comers Coco Gauff and Emma Raducanu, will all be on display in February.
Raducanu and Gauff will take on each other in the second round of the 2023 Australian Open on January 18.
In 2022, Emma Raducanu finished her first full year of touring. Even though the rising star was unable to perform with the same enchantment on the courts as she did in 2021
Raducanu had to withdraw from the Transylvania Open and Billie Jean King Cup Finals after injuring her right wrist.
In the most recent photo shoot campaign for the German automaker Porsche, Emma Raducanu was stunning.
Raducanu went up against Yanina Wickmayer in the second round and won 6-3, 7-5 after a strong service game.
Emma Raducanu and Moyuka Uchijima will face each other in the first round of the 2022 WTA Korea Open on September 20.