Premier League Clubs must have at least four positive cases within their squad to secure suspension from now on.
Tottenham Hotspur manager Antonio Conte had plenty to say after his side lost to Chelsea in the Premier League on Sunday (January 23).
Burnley have plenty of injuries and their top goalscorer Maxwell Cornet is currently at the Africa Cup of Nations.
Rafael Benitez's final fixture in charge at Everton was their 2-1 loss in the Premier League to relegation strugglers Norwich City.
Chelsea boss Thomas Tuchel was left frustrated after a 1-1 draw against Brighton on Wednesday.
The biggest blow will be in form of the Portuguese playmaker - Bruno Fernandes. He will be unavailable due to a one-match suspension.